By Bhvishya Patel, London ENGLAND
Volunteers for an experimental coronavirus vaccine trial have received their first doses
as scientists desperately try to fight the illness which has now claimed
the lives of 18,738 in the UK.
Half of the volunteers will be injected with the coronavirus vaccine which is made from a weakened version of the common cold virus from chimpanzees |
Scientists at the Jenner Institute,
University of Oxford, have begun the first human trial in Europe by administering
the trial injections, which were developed in under three months, to more than
800 volunteers on Thursday.
And Health Secretary Matt Hancock has
insisted that Britons will be first in the queue for any successful
UK-developed vaccine from the £42 million programmes.
But Downing Street is refusing to make
any promises over who will benefit first from the drug due to concerns another
country might produce one first.
A Department of Health and Social Care source
told the Telegraph: 'If Britain
is first to develop a vaccine he wants to make sure British people have first
refusal.'
The trial will see half of the candidates
injected with the coronavirus vaccine, made from a weakened version of the
common cold virus from chimpanzees, while the other half will be given a
meningitis vaccine.
The volunteers will not be told which vaccine
they have received.
Microbiologist and volunteer Elisa Granato told the BBC: 'Well I'm a
scientist so of course I want to try and support the scientific process
wherever I can and since I don't study viruses I felt a bit useless these days
so I felt this is a very easy way for me to support the cause.'
Researchers at the institute, who created the vaccine using technology
they have previously used for successfully treating diseases such as Mers and
Ebola, are 'confident' that the trial will pave the way for millions of
vaccines being made available to the public by September.
By taking a version of the common cold
virus, ChAdOx1, and modifying it so that it does not grow in humans,
scientists hope the process will activate an immune response that will protect
humans and destroy the virus.
Professor of vaccinology at the Jenner Institute, Sarah Gilbert, who led
the pre-clinical research, said she was 80 per cent confident about the outcome
of the vaccine.
She told the BBC: 'Personally I have a high
degree of confidence in this vaccine.
'Of course, we have to test it and get data from humans. We have to
demonstrate it actually works and stops people getting infected with
coronavirus before using the vaccine in the wider population.'
Lydia Guthrie, who is also taking part in the
trial, told BBC Radio 4's The World At One programme: 'They've (the clinical
team) been very clear with participants about the potential risk, and vaccine
trials are very carefully regulated, so we've had to give explicit consent at
every step of the way.
'They're really clear with us that as
participants we can pull out at any time if we change our minds.'
Once the vaccine, which is made from a
weakened version of the common cold virus from chimpanzees, is injected into
participants it will prompt the body to produce antibodies and T-cells which
will in turn destroy the virus.
Scientists, who will pursue a larger trial of
about 5,000 volunteers in the coming months, will know if the vaccine has
worked by looking at the number of candidates who become infected with the
virus from the two groups.
The first human trial comes as Britain announced another 616 coronavirus
victims today, taking the total number of fatalities in the UK to 18,738.
Another 4,583 people have tested positive for
the virus in the past 24 hours, meaning 138,078 have now been officially diagnosed.
The number of positive tests has remained stable this week and appears to be
plateauing.
NHS England confirmed a further 514 people
have died with COVID-19 and another 102 deaths were announced across Scotland,
Wales and Northern Ireland.
Today's figure marks a fall of 37 per cent
from the worst day in Britain's statistics, April 10, when 980 people were
confirmed to have died - and is lower than the 759 recorded
yesterday.
No comments:
Post a Comment